The Science Of OS-01
Boosts epidermal thickness for a stronger-looking skin barrier.
Supports natural collagen production for firmer-looking skin.
Helps reduce visible signs of aging.
Supports cellular repair for healthier-looking skin.
See Why Customers Love OS-01 BODY
"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.
Led By Science Not Hype
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Rigorous R&D Platform
End-to-end product development run by our in-house team of scientists.
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Peer-Reviewed Publications
The gold standard for scientific research and in skin care.
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Scientifically Validated Claims
Quantified by our proprietary MolClock and Skin Age Modeling methods.
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Ongoing Clinical Studies
Conducted by independent, third-party research organizations.
WHAT CAUSES AGING?
A Main Culprit: Cellular Senescence
With age and exposure to environmental stressors, some cells enter a dysfunctional state known as senescence.04
Often called “zombie cells,” these cells release inflammatory factors that trigger nearby healthy cells to become senescent. As the body becomes less efficient at clearing them out, their buildup leads to:04
Powered By OS-O1
The first peptide clinically shown to help reverse skin’s biological age by preventing the buildup of senescent cells.
The Future Of Skin Health Backed By Board-Certified Advisors
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Suneel Chilukuri, MD, FAAD, FACMS
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Carolyn Jacob, MD
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Joely Kaufman, MD
ONESKIN LONGEVITY SCIENCETM
The Science Behind OS-01 BODY
Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.
To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.01
Shown in lab studies onex vivohuman skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.
5 active ingredients complement the OS-01 peptide
ONESKIN CO-FOUNDER & CEO
Carolina Reis Oliveira, PhD
Fascinated with biology from a young age, Carolina knew she’d have a future in science. A fearless leader with a passion for longevity and living life to the fullest, she embarked on an ambitious goal — to delay the onset of age-related diseases by targeting aging itself. This led her to earn degrees in stem cell biology and tissue engineering, and a doctorate in immunology. Then, determined to translate her academic achievements into real-world impact, Carolina left her native Brazil for Silicon Valley, co-founding OneSkin in 2016. As Chief Executive Officer, Carolina and her team spearhead research and development, creating molecules that target cellular aging, including their pioneering innovation, the OS-01 peptide.
ONESKIN CO-FOUNDER & CHIEF SCIENTIFIC OFFICER
Alessandra Zonari PhD
Alessandra isn’t your typical scientist. She’s a visionary with a passion for longevity, skin regeneration, and the occasional karaoke jam. Growing up in a close-knit family in Brazil, Alessandra saw her grandparents struggle with age-related diseases and soon became fascinated by the possibility of using stem cells to redefine the aging process. After earning degrees in biology and stem cell biology, and a doctorate in skin regeneration and tissue engineering, Alessandra joined OneSkin in 2017 as a founding member and Chief Scientific Officer. Her contributions include 20+ papers, 3 patents, and the development of their proprietary OS-01 peptide.
CO-FOUNDER
Mariana Boroni PhD
Mariana Boroni, PhD, co-founder, earned her Master’s degree in biochemistry, and her PhD in bioinformatics with an emphasis in genomics at the Federal University of Minas Gerais. Mariana did her post-doctoral at the Ludwig-Maximilians University of Munich in Germany, and worked as a visiting researcher at the University of Birmingham, England. Mariana is Head of the Bioinformatics and Computational Biology Lab at the Brazilian National Cancer Institute (INCA). Together with the OneSkin team, Mariana developed the company’s proprietary skin-specific DNAm age predictor. Mariana is co-inventor of four patents, and has published more than 20 peer-reviewed papers in scientific journals.
CO-FOUNDER
Juliana Carvalho PhD
Juliana Carvalho, PhD, earned her Master’s degree in biochemistry and immunology, and her PhD in molecular biology from the Federal University of Minas Gerais in Brazil. In 2015, Juliana joined the Catholic University of Brasilia as a professor of pathology, and in 2019, she joined the Faculty of Medicine at the University of Brasilia. As an advisor to students earning their Masters and PhD degrees in science at both the University of Brasilia and the Catholic University of Brasilia, Juliana guides the newest scientists of our generation. Juliana is co-inventor of four patents, and has published 34 peer-reviewed papers in scientific journals (and counting!).
Reduce Biological Age By -2.5 Years
Measured in lab studies on human skin samples using MolClock, OneSkin’s proprietary algorithm that predicts skin’s biological age. Skin treated with the OS-01 peptide displayed a significant decrease in skin’s biological age compared to skin with no treatment. (Zonari, A., et al. npj Aging, 2023) (Boroni, M. et al. Clinical Epigenetics, 2020) Note: In npj Aging publication,"Pep 14" = OS-01 peptide
Customer Reviews
FAQS
What is the pH of OS-01 BODY?
What is the pH of OS-01 BODY?
OS-01 BODY pH is 5.5-7.0
Can I use this OS-01 BODY on my face?
Can I use this OS-01 BODY on my face?
No, we do not recommend using OS-01 BODY on your face. We specifically designed the OS-01 BODY formula for optimal absorption of the OS-01 peptide and included active ingredients and supporting oils better suited for the skin on your body.
How long will OS-01 BODY last?
How long will OS-01 BODY last?
The 250 ml bottle of OS-01 BODY will last approximately 1-2 months, when used as directed.
What is the shelf life of OS-01 BODY? How should it be stored?
What is the shelf life of OS-01 BODY? How should it be stored?
OS-01 BODY has a shelf life of 24 months.
All OneSkin products can be stored at room temperature away from direct sunlight.
How is OS-01 BODY formulated specifically for the skin on the body, except the face?
How is OS-01 BODY formulated specifically for the skin on the body, except the face?
OS-01 BODY is formulated with ingredients like centella asiatica extract, sulforaphane, and ceramides which heal, hydrate, and improve the skin on the body. OS-01 BODY also contains a concentration of our peptide which benefits the skin on the body.